SU-16F is primarily utilized in biological research as a potent and selective inhibitor of STAT3 (Signal Transducer and Activator of Transcription 3). It is employed in studies focused on understanding the role of STAT3 in various cellular processes, including cell growth, survival, and differentiation. Researchers use SU-16F to investigate its potential in cancer therapy, as STAT3 is often implicated in tumor progression and resistance to apoptosis. Additionally, it is applied in preclinical studies to explore its effects on inflammation and immune responses, given STAT3's involvement in these pathways. Its specificity makes it a valuable tool for dissecting STAT3-related signaling mechanisms in both normal and diseased states.