PK11007 is primarily utilized in research settings as a selective antagonist for the sigma-2 receptor. This makes it a valuable tool in studying the role of sigma-2 receptors in various biological processes, particularly in cancer research. It is often employed to investigate the mechanisms of cell proliferation, apoptosis, and tumor growth inhibition. Additionally, PK11007 is used in neuropharmacology studies to explore its potential therapeutic effects in neurodegenerative diseases and psychiatric disorders. Its ability to modulate sigma-2 receptor activity also makes it a candidate for developing imaging agents to detect and monitor cancer progression.