Used primarily in research settings as a potent and selective antagonist for the 5-HT2B receptor, making it valuable in studying serotonin receptor subtypes and their roles in cardiovascular function and neuropharmacology. It has been utilized in preclinical studies to investigate the mechanisms underlying drug-induced valvular heart disease, as activation of 5-HT2B receptors has been linked to cardiac fibrosis. Due to its high selectivity, it helps differentiate 5-HT2B-mediated effects from those involving other serotonin receptors, supporting the development of safer therapeutic agents targeting the central nervous system or cardiovascular system.