1-(5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine fumarate
97%
Reagent
Code: #188128
CAS Number
881681-01-2
science Other reagents with same CAS 881681-01-2
blur_circular Chemical Specifications
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Molecular Information
Weight
461.46 g/mol
Formula
C₂₁H₂₀FN₃O₆S
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Registry Numbers
MDL Number
MFCD18633280
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Storage & Handling
Storage
Store in an inert gas at room temperature
description Product Description
Used in pharmaceutical research as a potent and selective antagonist for serotonin receptors, particularly 5-HT6, showing potential in the development of cognitive enhancers for neurodegenerative disorders such as Alzheimer's disease. Demonstrates good blood-brain barrier penetration and oral bioavailability in preclinical models, making it a valuable candidate in studies targeting memory impairment and neurobehavioral conditions. Also employed in structure-activity relationship (SAR) studies to optimize receptor binding affinity and selectivity in central nervous system drug discovery.
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