tert-Butyl 4-hydroxy-2-(trifluoromethyl)piperidine-1-carboxylate

95%

Reagent Code: #151802
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CAS Number 1785759-35-4

science Other reagents with same CAS 1785759-35-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 269.26 g/mol
Formula C₁₁H₁₈F₃NO₃
badge Registry Numbers
MDL Number MFCD27986421
inventory_2 Storage & Handling
Storage Room temperature, dry

description Product Description

Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of central nervous system (CNS) agents. Its piperidine backbone features a 4-hydroxy group for potential derivatization and a 2-trifluoromethyl substituent that enhances metabolic stability and lipophilicity, making it valuable in drug design for improving bioavailability and blood-brain barrier penetration. The tert-butyl carbamate (Boc) protecting group allows for controlled functionalization of the nitrogen during multi-step syntheses. Commonly employed in the preparation of selective receptor modulators, including those targeting serotonin and dopamine receptors. Also utilized in the creation of bioactive molecules for treating psychiatric and neurological disorders due to its favorable stereochemistry and structural rigidity.

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Size Availability Unit Price Quantity
inventory 25mg
10-20 days ฿4,850.00
inventory 100mg
10-20 days ฿10,470.00
inventory 250mg
10-20 days ฿17,470.00

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tert-Butyl 4-hydroxy-2-(trifluoromethyl)piperidine-1-carboxylate
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Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of central nervous system (CNS) agents. Its piperidine backbone features a 4-hydroxy group for potential derivatization and a 2-trifluoromethyl substituent that enhances metabolic stability and lipophilicity, making it valuable in drug design for improving bioavailability and blood-brain barrier penetration. The tert-butyl carbamate (Boc) protecting group allows for controlled functionalization of the ni

Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of central nervous system (CNS) agents. Its piperidine backbone features a 4-hydroxy group for potential derivatization and a 2-trifluoromethyl substituent that enhances metabolic stability and lipophilicity, making it valuable in drug design for improving bioavailability and blood-brain barrier penetration. The tert-butyl carbamate (Boc) protecting group allows for controlled functionalization of the nitrogen during multi-step syntheses. Commonly employed in the preparation of selective receptor modulators, including those targeting serotonin and dopamine receptors. Also utilized in the creation of bioactive molecules for treating psychiatric and neurological disorders due to its favorable stereochemistry and structural rigidity.

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