tert-Butyl 4-hydroxy-2-(trifluoromethyl)piperidine-1-carboxylate
95%
science Other reagents with same CAS 1785759-35-4
blur_circular Chemical Specifications
description Product Description
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of central nervous system (CNS) agents. Its piperidine backbone features a 4-hydroxy group for potential derivatization and a 2-trifluoromethyl substituent that enhances metabolic stability and lipophilicity, making it valuable in drug design for improving bioavailability and blood-brain barrier penetration. The tert-butyl carbamate (Boc) protecting group allows for controlled functionalization of the nitrogen during multi-step syntheses. Commonly employed in the preparation of selective receptor modulators, including those targeting serotonin and dopamine receptors. Also utilized in the creation of bioactive molecules for treating psychiatric and neurological disorders due to its favorable stereochemistry and structural rigidity.
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