Used in research as a potent and selective antagonist for serotonin receptors, particularly 5-HT3 receptor subtype. It serves as a pharmacological tool to study the role of serotonin signaling in the central nervous system and gastrointestinal tract. Commonly applied in neuroscience and neuropharmacology studies to investigate emesis, anxiety, and gut motility. Also utilized in radiolabeled form to map receptor distribution in tissues. Its high selectivity makes it valuable in developing assays for drug screening and receptor binding studies.