A-582941 is utilized in neuroscience research as a selective positive allosteric modulator (PAM) of the α7 nicotinic acetylcholine receptor (nAChR). It enhances receptor activity without directly activating it, aiding studies on cognitive processes including memory, attention, and sensory gating. Commonly employed in preclinical models for schizophrenia, Alzheimer's disease, ADHD, and other cognitive disorders to investigate potential therapeutic benefits. Also applied in in vitro assays and animal studies to evaluate receptor modulation, synaptic plasticity, and neuroprotective effects.