SB-269970 is primarily used in research settings to study the role of serotonin receptors, specifically the 5-HT7 receptor, in various physiological and pathological processes. It acts as a selective antagonist, blocking the activity of these receptors, which helps scientists understand their function in the central nervous system. This compound has been instrumental in exploring the potential involvement of 5-HT7 receptors in conditions such as depression, anxiety, and sleep disorders. Additionally, it has been used to investigate the receptor's role in cognitive processes and memory formation. Research involving SB-269970 has also extended to studying its effects on circadian rhythms and neurodevelopmental disorders, providing insights into potential therapeutic targets for these conditions.