Irindalone is primarily utilized in research settings as a selective antagonist for serotonin receptors, particularly the 5-HT2A subtype. Its application is significant in studying the role of these receptors in various physiological and pathological processes, including mood regulation, anxiety, and psychosis. Researchers employ irindalone to better understand serotonin signaling pathways and to evaluate potential therapeutic targets for psychiatric disorders. Additionally, it is used in pharmacological experiments to investigate the effects of serotonin receptor blockade, aiding in the development of new drugs for mental health conditions.