4-(Aminomethyl)-2-fluorobenzonitrile
97%
Reagent
Code: #133199
CAS Number
368426-73-7
blur_circular Chemical Specifications
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Molecular Information
Weight
150.15 g/mol
Formula
C₈H₇FN₂
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Registry Numbers
MDL Number
MFCD06658314
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Storage & Handling
Storage
Room temperature, light-proof, inert gas
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of central nervous system (CNS) agents. Its structure allows for the formation of bioactive molecules, especially in the production of serotonin receptor modulators. Commonly employed in the preparation of selective 5-HT1F agonists for the treatment of migraine without vasoconstrictive effects. The fluorinated aromatic ring and aminomethyl group enhance binding affinity and metabolic stability, making it valuable in medicinal chemistry for optimizing drug candidates. Also utilized in the creation of novel fluorinated analogs in drug discovery programs targeting neurological disorders.
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