Nelotanserin is primarily researched for its potential therapeutic applications in treating neurological and psychiatric disorders. It acts as an inverse agonist on specific serotonin receptors, which makes it a candidate for addressing conditions like Parkinson's disease psychosis and REM sleep behavior disorder. Its mechanism of action helps in modulating serotonin signaling, which is crucial for managing hallucinations, delusions, and sleep disturbances associated with these conditions. Clinical studies are ongoing to evaluate its efficacy and safety in improving symptoms and enhancing the quality of life for patients with these disorders.