Ketanserin is primarily used in research and clinical settings as a selective antagonist for serotonin receptors, particularly the 5-HT2A subtype. It has been studied extensively for its potential to modulate serotonin-related pathways, which are implicated in various physiological and pathological processes. In cardiovascular research, ketanserin has been explored for its ability to lower blood pressure by blocking serotonin-induced vasoconstriction, making it a candidate for managing hypertension. Additionally, it has been investigated for its role in psychiatric disorders, such as anxiety and depression, due to its influence on serotonin signaling. Ketanserin has also been used in studies related to platelet aggregation, as serotonin plays a role in this process. Its applications extend to understanding serotonin's involvement in conditions like migraines, Raynaud's phenomenon, and certain types of cancer. While not widely used in clinical practice, ketanserin remains a valuable tool in pharmacological research for dissecting serotonin receptor functions.