RHO-15 is primarily utilized in research settings, particularly in the field of neuroscience and pharmacology. It is known for its role as a selective antagonist of the 5-HT1A receptor, which makes it valuable in studying serotoninergic systems and their influence on various physiological and behavioral processes. Researchers employ RHO-15 to investigate the mechanisms of anxiety, depression, and other mood disorders, as well as to explore potential therapeutic interventions. Its specificity allows for precise modulation of serotonin signaling, aiding in the understanding of receptor function and the development of targeted treatments for psychiatric conditions. Additionally, RHO-15 is used in experimental models to dissect the role of 5-HT1A receptors in cognitive functions, such as memory and learning, providing insights into the complex interplay between serotonin and brain activity.