8-OH-DPAT is primarily used in neuroscience research as a selective agonist for serotonin receptors, specifically the 5-HT1A subtype. It is widely employed in studies investigating the role of serotonin in various brain functions, including mood regulation, anxiety, and depression. Researchers use it to explore the mechanisms of serotonin signaling and its impact on behavior, cognition, and emotional responses. Additionally, 8-OH-DPAT is utilized in animal models to study the effects of 5-HT1A receptor activation on locomotor activity, thermoregulation, and neuroendocrine functions. Its ability to modulate serotonin pathways makes it a valuable tool for understanding psychiatric disorders and developing potential therapeutic interventions.