Nafamostat Mesylate is primarily used as an anticoagulant in medical settings, particularly during procedures like hemodialysis to prevent blood clotting. It is also effective in treating acute pancreatitis by inhibiting proteases that contribute to the inflammation and tissue damage associated with the condition. Additionally, it has shown potential in managing disseminated intravascular coagulation (DIC), a complex disorder where blood clotting and bleeding occur simultaneously. Recently, its application has expanded to antiviral research, where it has been studied for its ability to inhibit viral entry into cells, offering potential benefits in treating certain viral infections. Its broad-spectrum protease inhibition makes it a versatile compound in both therapeutic and experimental contexts.