UAMC00039 dihydrochloride is primarily utilized in research settings, particularly in the study of cancer and inflammatory diseases. It functions as a selective inhibitor of fibroblast activation protein (FAP), which is often overexpressed in the stroma of various cancers. By inhibiting FAP, it helps researchers understand the role of this protein in tumor growth and metastasis, potentially leading to the development of targeted cancer therapies. Additionally, its application extends to investigating the modulation of the tumor microenvironment, which is crucial for advancing immunotherapy approaches. The compound is also explored for its potential in reducing fibrosis and inflammation in chronic diseases, providing insights into therapeutic strategies for conditions like pulmonary fibrosis and rheumatoid arthritis.