TM-5441 is primarily studied for its potential applications in medical research, particularly in the field of cancer therapy. It functions as an inhibitor of plasminogen activator inhibitor-1 (PAI-1), which plays a role in tumor growth and metastasis. By targeting PAI-1, TM-5441 may help reduce the spread of cancer cells and inhibit angiogenesis, the process by which tumors develop new blood vessels to support their growth. Additionally, it is being explored for its potential use in treating fibrotic diseases, as PAI-1 is also involved in the development of fibrosis in various tissues. Research is ongoing to evaluate its efficacy and safety in these therapeutic areas.