PHTPP is primarily used as a selective estrogen receptor modulator (SERM) in scientific research. It is often employed in studies to investigate the role of estrogen receptors in various biological processes. Researchers utilize PHTPP to block the activity of estrogen receptor beta (ERβ) selectively, allowing them to study the specific functions and mechanisms of this receptor subtype. This compound is valuable in understanding the differential effects of estrogen receptors in diseases such as cancer, osteoporosis, and cardiovascular disorders. Additionally, PHTPP is used in pharmacological experiments to explore potential therapeutic applications targeting ERβ, aiding in the development of treatments for hormone-related conditions. Its specificity makes it a crucial tool in endocrinology and molecular biology research.