Atipamezole is primarily used as a reversal agent for sedation or anesthesia induced by alpha2-adrenergic agonists such as dexmedetomidine and medetomidine. It is commonly administered in veterinary medicine to rapidly restore consciousness and motor function in animals, especially dogs and laboratory rodents. By competitively blocking alpha2-adrenergic receptors, atipamezole effectively counteracts the central nervous system and cardiovascular effects of these sedatives. It allows for quick recovery with minimal stress, making it valuable in clinical and research settings where controlled sedation is required. The compound is available in injectable form and can be given intramuscularly or subcutaneously, with effects typically observed within minutes. Its high selectivity and potency make it a reliable choice for emergency or scheduled reversal of sedation.