Ammonium sulfamate is widely used as a herbicide for controlling weeds and woody plants in non-crop areas such as industrial sites, railways, and fence lines. It is effective against a broad spectrum of vegetation, including hard-to-kill plants like poison ivy and brambles. The compound works by interfering with plant growth, leading to the eventual death of the treated vegetation.

In addition to its herbicidal properties, it serves as a flame retardant in various materials, including paper, textiles, and wood products. It helps reduce flammability by releasing non-flammable gases when exposed to heat, thereby slowing down the spread of fire.

It is also used in the synthesis of other chemicals, particularly in the production of sulfamic acid and its derivatives, which have applications in cleaning agents, descaling products, and water treatment. Its ability to act as a stabilizer in certain industrial processes further enhances its utility in chemical manufacturing.

Overall, ammonium sulfamate is valued for its versatility in agriculture, fire safety, and industrial applications.