Ammonium trifluoromethanesulfonate is widely used in organic synthesis as a catalyst or reagent due to its strong acidic properties. It is particularly effective in promoting esterification, alkylation, and acylation reactions, enabling the formation of complex organic molecules with high efficiency. In the field of electrochemistry, it serves as an electrolyte additive in lithium-ion batteries, enhancing ionic conductivity and improving battery performance. Additionally, it is utilized in the production of specialty chemicals and polymers, where its stability and reactivity make it a valuable component in various industrial processes. Its applications also extend to analytical chemistry, where it is used in mass spectrometry as a matrix additive to improve the ionization of analytes.