Used as a counterion in pharmaceutical formulations to improve the solubility and stability of poorly water-soluble drugs, particularly in iodinated diagnostic imaging agents. Commonly found in contrast media for X-ray, CT scans, and angiography, where it helps enhance image clarity by increasing the solubility of active iodinated compounds. Also utilized in some ophthalmic solutions due to its low toxicity and favorable safety profile. As a weak base derived from glucose, it provides buffering capacity in formulations, contributing to improved patient tolerance.