Used as a mordant in textile dyeing to help fix dyes onto fabrics, especially with natural fibers. Acts as a drying agent in paints and varnishes due to its catalytic effect on oxidation of drying oils. Employed in the production of other lead compounds for industrial applications, including the manufacture of lead glass or crystal glass to increase density and refractive index, enhancing brilliance and light transmission.

Historically used in cosmetics, hair dyes, and skin care products like skin-lightening creams, though this practice has declined due to toxicity concerns, as lead can be absorbed into the body, accumulate in organs, and cause chronic poisoning affecting the nervous system, kidneys, and reproductive system.

Occasionally used in laboratory settings as a reagent for qualitative analysis of anions like sulfides and chromates, forming characteristic precipitates. Also found use in the preparation of lead-based coatings and in some electroplating processes. In chemical synthesis, it serves as a starting material for other lead compounds, but must be handled with high caution due to its toxicity and environmental impact.