Cesium fluoride is widely used in organic synthesis as a source of fluoride ions due to its high solubility in polar solvents and strong nucleophilic character. It is particularly effective in desilylation reactions, where it removes silyl protecting groups from alcohols, amines, and other functional groups under mild conditions. It serves as a catalyst or reagent in cross-coupling reactions, including palladium-catalyzed transformations, enhancing reaction rates and selectivity. In materials science, cesium fluoride is employed in the fabrication of semiconductor devices and perovskite solar cells, where it improves electron transport and device efficiency. It is also used in the preparation of radiopharmaceuticals, especially in nucleophilic fluorination reactions involving fluorine-18 for positron emission tomography (PET) imaging. Its low lattice energy and high ionic character make it advantageous in solid-state chemistry and molten salt applications.