Cesium fluoride is widely used in organic synthesis as a source of fluoride ions due to its high solubility and reactivity. It is particularly effective in desilylation reactions, where it removes silyl protecting groups from alcohols, amines, and other functional groups under mild conditions. It serves as a catalyst or reagent in nucleophilic substitution reactions, including the preparation of fluoroorganic compounds. In materials science, cesium fluoride is used in the deposition of thin films and in the fabrication of semiconductor devices, where it improves electron injection in organic light-emitting diodes (OLEDs). It is also employed in analytical chemistry for sample preparation in mass spectrometry and elemental analysis.