Ru-MACHO is primarily used as a highly efficient catalyst in hydrogenation reactions, particularly for the reduction of esters to alcohols under mild conditions. Its application is significant in organic synthesis, where it enables the conversion of complex ester-containing molecules into valuable alcohols with high selectivity and yield. This makes it a crucial tool in the production of pharmaceuticals, fine chemicals, and agrochemicals. Additionally, Ru-MACHO is employed in the development of sustainable chemical processes due to its ability to operate at lower temperatures and pressures, reducing energy consumption and environmental impact. Its versatility also extends to asymmetric hydrogenation, contributing to the synthesis of chiral compounds used in drug development and other industries.