Used as a highly efficient catalyst in cross-coupling reactions, particularly in Suzuki–Miyaura and Heck reactions, enabling the formation of carbon–carbon bonds in pharmaceutical and fine chemical synthesis. Its sterically hindered, electron-rich ligand environment enhances catalytic activity and stability, allowing reactions to proceed under mild conditions with high selectivity. Effective for coupling aryl chlorides, which are typically less reactive, making it valuable for constructing complex aromatic systems in drug development and materials science.