Hydroxyfasudil is primarily used in research and medical applications due to its role as a potent inhibitor of Rho-associated kinase (ROCK). It is widely studied for its potential therapeutic effects in treating cardiovascular diseases, as it helps to relax blood vessels and improve blood flow. This makes it a promising candidate for managing conditions like hypertension and cerebral vasospasm. Additionally, it is being explored in neurological research for its neuroprotective properties, which could aid in treating neurodegenerative disorders such as Alzheimer's disease. Its anti-fibrotic effects are also being investigated for applications in reducing tissue scarring and fibrosis in organs like the liver and lungs.