Used as a chiral catalyst in asymmetric synthesis, particularly in enantioselective C–H functionalization reactions. It enables high enantioselectivity in the insertion of carbenoids into C–H bonds, making it valuable in the synthesis of complex organic molecules, including pharmaceuticals and natural products. Its robust structure and fluorinated ligands enhance both reactivity and selectivity under mild conditions. Commonly applied in cyclization, cyclopropanation, and Si–H bond insertion reactions where stereochemical control is critical.