Widely used as a catalyst in organic synthesis, particularly for C–H bond functionalization reactions. It enables selective transformations of inert carbon-hydrogen bonds into more complex structures such as esters, amines, and other functional groups under mild conditions. Commonly employed in cyclopropanation, insertion reactions, and asymmetric synthesis, especially with diazo compounds. Its high selectivity and efficiency make it valuable in pharmaceutical and fine chemical industries for building complex molecular architectures. The bulky pivalate ligands enhance catalyst stability and influence stereoselectivity, making it preferred over other rhodium carboxylates in certain transformations.