Sulforhodamine 101 DHPE is widely used as a fluorescent lipid probe in biological research. It is particularly valuable for studying membrane dynamics and lipid trafficking in cells. The compound is incorporated into lipid bilayers, allowing researchers to visualize and track the movement of membranes in real time using fluorescence microscopy. Its bright and stable fluorescence makes it suitable for long-term imaging experiments. Additionally, it is used in model membrane systems to investigate lipid interactions and membrane fusion processes. The probe is also employed in studies of endocytosis and exocytosis, providing insights into cellular transport mechanisms. Its compatibility with live-cell imaging further enhances its utility in understanding cellular processes at the molecular level.