ZCL278 is primarily utilized in biochemical research as a selective inhibitor of Cdc42, a small GTPase protein involved in regulating cell signaling pathways. Its application is significant in studying cellular processes such as cytoskeletal reorganization, cell migration, and proliferation. Researchers use ZCL278 to investigate the role of Cdc42 in various diseases, including cancer, immune disorders, and neurological conditions. By inhibiting Cdc42 activity, ZCL278 helps elucidate its function in cellular mechanisms and potential therapeutic targets. This compound is particularly valuable in experimental settings where precise modulation of Cdc42-dependent pathways is required to understand its biological impact.