Diclofenine hydrochloride is primarily used in research settings to study its effects on the central nervous system. It acts as a dopamine and norepinephrine reuptake inhibitor, making it valuable in investigations related to neurotransmitter regulation and potential treatments for conditions like depression and Parkinson's disease. Its application extends to exploring mechanisms of addiction and reward pathways in the brain. Additionally, it has been utilized in pharmacological studies to understand its stimulant properties and potential therapeutic benefits. However, its clinical use is limited due to safety concerns and side effects.