Used in immunological research to detect and analyze TLR4 (Toll-like receptor 4) expression on mouse immune cells. Helps study innate immune responses, particularly in macrophages and dendritic cells, when activated by bacterial lipopolysaccharide (LPS). Commonly applied in flow cytometry to identify cell surface TLR4 levels and monitor immune activation. Supports research into inflammatory diseases, sepsis, vaccine development, and signaling pathways involving TLR4-mediated cytokine production.