Used in cancer immunotherapy research, particularly for targeting B-cell malignancies. It serves as a reference antibody in the development of anti-CD37 therapeutics, aiding in the evaluation of binding affinity, specificity, and functional activity of novel antibody-based drugs. Employed in flow cytometry, immunohistochemistry, and in vitro assays to detect CD37 expression on tumor cells. Supports the calibration and validation of diagnostic tests and therapeutic monitoring tools. Also utilized in antibody-drug conjugate (ADC) research, where it helps optimize payload delivery to CD37-positive cancer cells.