Used in research and therapeutic development for immune-related diseases due to its ability to modulate the LIGHT pathway, which plays a key role in T-cell activation and inflammation. It is investigated for potential in treating autoimmune conditions such as rheumatoid arthritis, inflammatory bowel disease, and psoriasis by blocking the interaction between LIGHT and its receptors (HVEM, LTβR, and DcR3), thereby reducing inflammatory responses. Also employed as a reference reagent in bioassays to evaluate the potency and specificity of other anti-LIGHT antibodies or drug candidates in preclinical studies.