Anti-Tau Reference Antibody (zagotenemab) is used as a research and development tool for neurological disorders involving tau protein, such as Alzheimer's disease. It identifies and binds to misfolded tau protein, a key pathological feature, allowing precise tracking of tau accumulation in brain tissue. Additionally, it serves as a reference standard for developing diagnostics, including immunoassays or biological imaging, to assess the efficacy of anti-tau therapies in laboratory and clinical trial settings.