Used in research and diagnostic applications to detect and neutralize the spike protein of Omicron subvariants BA.2, BA.2.75, BA.4, and BA.5 of SARS-CoV-2. Binds specifically to the S1 subunit of the viral spike protein, making it valuable for studying viral entry mechanisms and immune response. Employed in immunoassays, such as ELISA and flow cytometry, to quantify spike protein expression and evaluate antibody efficacy. Also supports development of therapeutic strategies by identifying epitopes conserved across multiple Omicron lineages. Useful in surveillance studies to monitor antigenic drift and assess cross-reactivity of immune responses.