Used in research and therapeutic development targeting the sphingosine-1-phosphate (S1P) signaling pathway, which plays a key role in immune cell regulation, inflammation, angiogenesis, and vascular integrity. This reference antibody serves as a critical tool for detecting and quantifying S1P in biological samples, enabling studies on S1P dynamics in disease models such as multiple sclerosis, cancer, and autoimmune disorders. It supports assay development for drug discovery, particularly in evaluating the efficacy of S1P receptor modulators. Due to its high specificity, it is also employed in pharmacokinetic and pharmacodynamic studies to monitor target engagement and pathway modulation in preclinical and clinical settings.