Used in research and therapeutic development targeting cardiovascular and metabolic diseases. Binds specifically to sortilin, a protein involved in lipid metabolism and regulation of low-density lipoprotein (LDL) receptor trafficking. By inhibiting sortilin function, this antibody helps increase clearance of LDL cholesterol from the bloodstream, showing potential for treating hypercholesterolemia and reducing atherosclerosis risk. Also investigated for roles in neurodegenerative conditions due to sortilin’s involvement in neuronal protein sorting and cell death pathways. Serves as a reference tool for developing biosimilars and evaluating sortilin-targeted drug efficacy.