Used in targeted cancer immunotherapy, particularly in CAR-T cell therapies where it binds to the ROBO1 receptor overexpressed in certain tumor cells. This antibody enables precise recognition of cancer cells, especially in solid tumors such as pancreatic, lung, and gastric cancers, facilitating their destruction by engineered T cells. Its high specificity enhances therapeutic efficacy while minimizing off-target effects. Also utilized as a research reagent for studying axon guidance pathways and tumor angiogenesis. Stable performance in immunohistochemistry and flow cytometry makes it valuable in diagnostic applications.