Used in research and development for targeting the Orai1 calcium channel, this antibody helps modulate calcium signaling in immune cells. It has potential therapeutic applications in autoimmune diseases such as psoriasis, rheumatoid arthritis, and lupus by suppressing abnormal T-cell activation. The antibody is also employed in preclinical studies to validate Orai1 as a drug target and to assess the efficacy of calcium signaling inhibitors. Its high specificity makes it a valuable tool for flow cytometry, immunoprecipitation, and functional assays in immunology and cell signaling research.