Used in research and therapeutic development for central nervous system (CNS) injuries such as spinal cord injury and stroke. The antibody targets the Nogo receptor (NgR), which plays a key role in limiting neuronal regeneration. By blocking NgR signaling, it promotes axonal growth and neural plasticity, supporting recovery of motor function in preclinical models. Investigated for potential in treating neurodegenerative conditions and enhancing neural repair after trauma. Also employed as a reference reagent in immunoassays and antibody development due to its well-characterized binding properties.