Used in research and development for inflammatory skin conditions such as Netherton syndrome and atopic dermatitis. Targets and inhibits KLK5 (kallikrein-related peptidase 5), a protease that is overactive in these diseases, leading to uncontrolled desquamation and inflammation. By neutralizing KLK5 activity, this antibody helps restore skin barrier function and reduce inflammation in preclinical models. Also serves as a tool antibody in assay development and target validation for dermatological therapeutics. Potential use in diagnostic applications to detect KLK5 levels in patient samples.