Used in clinical research to block interleukin-33 (IL-37), a cytokine involved in inflammatory responses. Investigated for treating autoimmune and allergic conditions such as asthma, atopic dermatitis, and chronic obstructive pulmonary disease (COPD). Helps modulate immune activity by inhibiting IL-33 signaling, reducing inflammation and tissue damage in affected areas. Evaluated in trials to assess safety and efficacy in suppressing disease progression linked to type 2 inflammation.