Used in research to study the function and signaling pathways of BTN1A1 (Butyrophilin Subfamily 1 Member A1) without inducing Fc-mediated effector functions due to the N297A mutation. This antibody is particularly valuable in immune modulation studies, especially in understanding regulatory mechanisms in T cell responses and its potential role in autoimmune diseases and cancer immunotherapy. The lack of Fc receptor binding allows for specific target neutralization or blocking while minimizing confounding immune activation, making it suitable for in vitro and in vivo functional assays.