Used in vaccine development and therapeutic research targeting the Omicron BA.2 variant of SARS-CoV-2. Serves as a key antigen for generating neutralizing antibodies in preclinical studies. Employed in ELISA and other immunoassays to detect spike-specific immune responses. Supports structural studies to understand virus-receptor interactions and antibody binding mechanisms. Facilitates screening of monoclonal antibodies and antiviral drugs aimed at blocking viral entry. The Fc tag enhances solubility and enables easy detection and purification in laboratory applications.