Used in vaccine development and diagnostic assays to detect neutralizing antibodies against the Omicron variant of SARS-CoV-2. Serves as a key antigen in serological testing to evaluate immune response post-infection or post-vaccination. Employed in research studies focused on viral entry mechanisms and antibody binding affinity. Enables high-throughput screening of therapeutic antibodies and antiviral drugs targeting the spike protein. Compatible with ELISA, surface plasmon resonance, and other binding assays due to the Avi and His tags that allow for easy immobilization and detection.