Used in vaccine development and antibody research to study immune response against the Omicron variant. Enables detection and quantification of neutralizing antibodies in diagnostic assays. Supports structural studies to understand spike protein interactions with the ACE2 receptor. Facilitates evaluation of therapeutic antibodies and antiviral drugs targeting the mutated RBD region. The Avi-His tag allows for efficient immobilization on biosensors and purification, making it suitable for high-throughput screening and binding assays.