Used in research and development of vaccines and therapeutics targeting the Monkeypox virus. The E8L protein with mFc tag facilitates studies on viral entry mechanisms and host immune responses. It serves as an antigen for antibody production and assay development, enabling detection and quantification of anti-monkeypox immune responses. The fusion with mFc enhances solubility and simplifies purification, making it suitable for high-throughput screening and structural analysis. Widely applied in immunogenicity studies and diagnostic tool development.